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The first biosynthetic studies of the azinomycins: acetate incorporation into azinomycin B†
Christophe Corre,Philip A. S. Lowden
Chemical Communications Pub Date : 03/19/2004 00:00:00 , DOI:10.1039/B400093E
Abstract

13 C-Labelled acetate efficiently labels the antitumour natural product azinomycin B, revealing a polyketide origin for the naphthoate fragment, that threonine is the probable precursor of the enol fragment, and that α-ketoglutarate is a probable precursor of the aziridine fragment.

Graphical abstract: The first biosynthetic studies of the azinomycins: acetate incorporation into azinomycin B
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