Synthesis of the core ring system of the stemona alkaloids by cascade condensation, cyclization, intramolecular cycloaddition†,10.1039/C0OB00408A

热搜：

Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Synthesis of the core ring system of the stemona alkaloids by cascade condensation, cyclization, intramolecular cycloaddition†

Adam. J. M. Burrell,Luke Watson,Nathaniel G. Martin,Niall Oram,Iain Coldham

Organic & Biomolecular Chemistry Pub Date : 08/24/2010 00:00:00 , DOI:10.1039/C0OB00408A

Abstract

Condensation of an aldehyde with an α-amino-ester, followed by a tandem process involving cyclization to a seven-membered ring, deprotonation to an intermediate azomethine ylide and intramolecular dipolar cycloaddition gave tricyclic products related to stenine and neostenine.