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Rh(iii)-catalyzed annulation of N-methoxybenzamides with ynesulfonamides at room temperature: a practical and efficient route to 4-aminoisoquinolone derivatives†
Guangying Tan,Xiaolei Huang,Qian Wu,Luo-Qiang Zhang,Jingsong You
RSC Advances Pub Date : 09/19/2014 00:00:00 , DOI:10.1039/C4RA09500F
Abstract

A practical and efficient Rh(III)-catalyzed annulation of N-methoxybenzamides with ynesulfonamides for the synthesis of 4-aminoisoquinolone derivatives has been developed under external-oxidant-free conditions at room temperature. This protocol features good functional group tolerance and excellent selectivity.

Graphical abstract: Rh(iii)-catalyzed annulation of N-methoxybenzamides with ynesulfonamides at room temperature: a practical and efficient route to 4-aminoisoquinolone derivatives
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