The solid-state assembly of two calixcyclitol derivatives bearing two or one rings (compounds 1 or 2, respectively) oxyfunctionalized with oxetane and hydroxyl functional groups has been structurally studied by X-ray crystallography. Calixcyclitol 1 can assemble to give a H-bonded layered (crystals 1A) or double-columnar (crystals 1B) structure with alternating polar and lipophilic zones. Calixcyclitol 2 gives a double-helical arrangement through the intermediacy of H2O and MeOH molecules.
