The rhodium-catalysed synthesis of pyrrolidinone-substituted (trialkylsilyloxy)acrylic esters†
Daniel L. Priebbenow,Carsten Bolm
RSC Advances Pub Date : 05/07/2013 00:00:00 , DOI:10.1039/C3RA41527A
Abstract

A method for the preparation of novel pyrrolidine substituted (trialkylsilyloxy)acrylic esters has been developed. The protocol involves a rhodium-catalysed O-insertion/rearrangement reaction between N-functionalised 2-pyrrolidinones and α-silyl α-diazoacetates to form the corresponding acrylic esters in moderate to high yields.

Graphical abstract: The rhodium-catalysed synthesis of pyrrolidinone-substituted (trialkylsilyloxy)acrylic esters