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Synthetic carbohydrate-based vaccines: synthesis of an L-glycero-D-manno-heptose antigen–T-epitope–lipopeptide conjugate
Chemical Communications Pub Date : 01/01/1900 00:00:00 , DOI:10.1039/A704127F
Abstract

A facile and highly efficient synthesis of a glycopeptidolipid containing a heptose sugar, a synthetic T-epitope and a synthetic immunoadjuvant is presented which represents an important step towards the development of a fully synthetic vaccine against Neisseria meningitidis.

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