The role of lipophilicity in transmembrane anion transport†
Vittorio Saggiomo,Sijbren Otto,Igor Marques,Vítor Félix,Tomás Torroba,Roberto Quesada
Chemical Communications Pub Date : 04/24/2012 00:00:00 , DOI:10.1039/C2CC31825C
Abstract

The transmembrane anion transport activity of a series of synthetic molecules inspired by the structure of tambjamine alkaloids can be tuned by varying the lipophilicity of the receptor, with carriers within a certain log P range performing best.

Graphical abstract: The role of lipophilicity in transmembrane anion transport