The solvent-free and catalyst-free conversion of an aziridine to an oxazolidinone using only carbon dioxide†
Chau Phung,Rani M. Ulrich,Mostafa Ibrahim,Nathaniel T. G. Tighe,Deborah L. Lieberman,Allan R. Pinhas
Green Chemistry Pub Date : 09/01/2011 00:00:00 , DOI:10.1039/C1GC15850C
Abstract

It has been found for the first time at room temperature that the reaction of an unactivated 2-alkyl or 2-aryl aziridine with carbon dioxide to generate the corresponding oxazolidinone does not need any form of catalysis or solvent to proceed in high yield, especially when using high speed ball milling.

Graphical abstract: The solvent-free and catalyst-free conversion of an aziridine to an oxazolidinone using only carbon dioxide