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Total synthesis of (±)-Vertine with Z-selective RCM as a key step†
Laetitia Chausset-Boissarie,Roman Àrvai,Graham R. Cumming,Céline Besnard,E. Peter Kündig
Chemical Communications Pub Date : 08/11/2010 00:00:00 , DOI:10.1039/C0CC01885F
Abstract

A concise total synthesis of the strained pentacyclic alkaloid (±)-Vertine has been achieved in eleven steps with the key steps being pelletierine condensation, Suzuki–Miyaura coupling, and ring-closing metathesis.

Graphical abstract: Total synthesis of (±)-Vertine with Z-selective RCM as a key step
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