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The organocatalytic two-step synthesis of diversely functionalized tricyclic tetrazoles†‡
Xiong Huang,Ping Li,Xin-Sheng Li,Dong-Cheng Xu,Jian-Wu Xie
Organic & Biomolecular Chemistry Pub Date : 08/23/2010 00:00:00 , DOI:10.1039/C0OB00272K
Abstract

The diversely functionalized tricyclic tetrazoles were synthesised from readily available substrates via intramolecular 1,3-dipolar cycloaddition as the key step in good yields (53–78% yield for two steps) with high enantioselectivities (81–99% ee).

Graphical abstract: The organocatalytic two-step synthesis of diversely functionalized tricyclic tetrazoles
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