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Additive-free selective methylation of secondary amines with formic acid over a Pd/In2O3 catalyst†
Caroline Genre,Idir Benaissa,Timothé Godou,Mathieu Pinault,Thibault Cantat
Catalysis Science & Technology Pub Date : 12/08/2021 00:00:00 , DOI:10.1039/D1CY01626A
Abstract

Formic acid is used as the sole carbon and hydrogen source in the methylation of aromatic and aliphatic amines to methylamines. The reaction proceeds via a formylation/transfer hydrogenation pathway over a solid Pd/In2O3 catalyst without the need for any additive.

Graphical abstract: Additive-free selective methylation of secondary amines with formic acid over a Pd/In2O3 catalyst
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