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Silver-decorated biodegradable polymer vesicles with excellent antibacterial efficacy†
Kaidian Zou,Qiuming Liu,Jing Chen,Jianzhong Du
Polymer Chemistry Pub Date : 08/19/2013 00:00:00 , DOI:10.1039/C3PY00966A
Abstract

We report the first enzymatically degradable polymer vesicle decorated with silver nanoparticles, which showed low cytotoxicity against human normal liver L02 cells near the minimum inhibitory concentrations (MICs) but excellent antibacterial efficacy against both Gram-negative and Gram-positive bacteria with quite low MICs of 3.56 μg mL−1 and 7.12 μg mL−1, respectively, exhibiting promising potential applications in nanomedicine.

Graphical abstract: Silver-decorated biodegradable polymer vesicles with excellent antibacterial efficacy
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