Fluorescent compounds with solid-state emission are expected to have broad applications in the development of optoelectronic devices. In this study, we develop O-BODIPY based fluorescent dyes which exhibit strong bimodal solid-state emissions across red and NIR regions. After one pot synthesis, samples are characterized by X-ray diffraction, cyclic voltammetry, UV-vis absorption, and fluorescence spectra. All the experimental data reveal the multiple excitation and efficient emission features in the aggregation states. Furthermore, the two produced probes can be successfully applied for tracking lysosomes in HeLa cells with low cytotoxicity.