Stereoselective synthesis of the hormonally active (25S)-Δ7-dafachronic acid, (25S)-Δ4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid†
René Martin,Frank Däbritz,Eugeni V. Entchev,Teymuras V. Kurzchalia,Hans-Joachim Knölker
Organic & Biomolecular Chemistry Pub Date : 10/17/2008 00:00:00 , DOI:
10.1039/B815064HAbstract
We report a stereoselective synthesis of the (25S)-cholestenoic-26-acids which are highly efficient ligands for the hormonal receptor DAF-12 in Caenorhabditis elegans.
