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Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(ii)macrocycle†
Ta-Sheng Andrew Tseng,Judith N. Burstyn
Chemical Communications Pub Date : 10/27/2008 00:00:00 , DOI:10.1039/B812183D
Abstract

An intercalator-linked macrocycle3,6-bis(dimethylamino)-10-(6-[1,4,7-triazacyclononane]hexyl) acridinium bromide was synthesized, its copper(II) complex was prepared, and the DNA cleavage activity of this metal complex was compared to that of the intercalator-free (Cu[9]aneN3)2+ complex.

Graphical abstract: Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(ii)macrocycle
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