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Synthesis of a hyaluronan neoglycopolymer by ring-opening metathesis polymerization†
Suri Iyer,Shyam Rele,Gabriela Grasa,Steven Nolan
Chemical Communications Pub Date : 05/30/2003 00:00:00 , DOI:10.1039/B301734F
Abstract

A hyaluronan (HA)-derived disaccharide was synthesized bearing an n-pentenyl spacer arm, which facilitated disaccharide derivatization with a norbornene template. Subsequent ring opening metathesis polymerization of the monomer produced an HA-mimetic neoglycopolymer of low polydispersity.

Graphical abstract: Synthesis of a hyaluronan neoglycopolymer by ring-opening metathesis polymerization
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