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Synthesis of indolines via a palladium/norbornene-catalyzed reaction of aziridines with aryl iodides†
Ce Liu,Yujie Liang,Nian Zheng,Bo-Sheng Zhang,Yuan Feng,Siwei Bi,Yong-Min Liang
Chemical Communications Pub Date : 03/12/2018 00:00:00 , DOI:10.1039/C8CC01062E
Abstract

A Pd- and norbornene-catalyzed domino procedure has been developed to synthesize indoline compounds. This reaction provides efficient access to indolines by employing aryl iodides with aziridines as new electrophiles. The transformation is scalable and tolerates a range of functional groups.

Graphical abstract: Synthesis of indolines via a palladium/norbornene-catalyzed reaction of aziridines with aryl iodides
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