Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions†
Anna Barosi,Petra Dunkel,Philippe Zeitoun,Isabelle Fitton,Clément Journé,Alberto Bravin,Antoine Maruani,Hamid Dhimane,Laurence Motte,Peter I. Dalko
Abstract
An efficient nano-sized delivery system is presented here allowing the immobilized, picolinium-tethered organic ligand to be released by X-ray irradiation. A marked difference was observed in the fragmentation efficiency by using conventional Cs-137 vs. pulsed sources.
