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Acceptorless dehydrogenative synthesis of 2-substituted quinazolines from 2-aminobenzylamine with primary alcohols or aldehydes by heterogeneous Pt catalysts†
Chandan Chaudhari,S. M. A. Hakim Siddiki,Masazumi Tamura
RSC Advances Pub Date : 10/09/2014 00:00:00 , DOI:10.1039/C4RA09205H
Abstract

CeO2-supported Pt nanoparticle catalysts enabled the acceptorless dehydrogenative synthesis of 2-substituted quinazolines from 2-aminobenzylamine with aliphatic and benzyl primary alcohols or aldehydes with low catalyst loading, wide substrate scope and good catalyst reusability, demonstrating the first acceptor-free and additive-free catalytic system for this reaction.

Graphical abstract: Acceptorless dehydrogenative synthesis of 2-substituted quinazolines from 2-aminobenzylamine with primary alcohols or aldehydes by heterogeneous Pt catalysts
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