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Synthesis of 2,2-difluoro-homoallylic alcohols via ring-opening of gem-difluorocyclopropane and aerobic oxidation by photo-irradiation in the presence of an organic pigment†
Hiroaki Takenaka,Yoshihiro Masuhara,Kent Narita
Organic & Biomolecular Chemistry Pub Date : 08/06/2018 00:00:00 , DOI:10.1039/C8OB01740A
Abstract

We found that aerobic oxidation took place after the visible light-mediated ring-opening reaction of gem-difluorocyclopropane in the presence of an organic dye and amine to furnish 2,2-difluoro-homoallylic alcohols in good yields.

Graphical abstract: Synthesis of 2,2-difluoro-homoallylic alcohols via ring-opening of gem-difluorocyclopropane and aerobic oxidation by photo-irradiation in the presence of an organic pigment
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