Yb(OTf)3 catalyzed new cascade reaction: a facile assembly of fused quinazolinones†
P. Mahesh Kumar,M. Appi Reddy,Md. Ferozuddin,M. Sreenivasulu,Ahamed A. Jafar,G. R. Krishna,C. Malla Reddy,D. Rambabu,K. Shiva Kumar,Sarbani Pal,Manojit Pal
Chemical Communications Pub Date : 08/19/2011 00:00:00 , DOI:10.1039/C1CC13695J
Abstract
A one-pot Yb(III)-mediated cascade reaction has been developed leading to small molecules based on a novel structural motif, i.e.quinazolin-4-one moiety fused with an isoquinoline ring, for potential inhibition of TNF-α.
