Chemical Communications Pub Date : 02/14/2006 00:00:00 , DOI:10.1039/B600819D
Abstract
A synthesis of the 9-oxa-3-thiabicyclo[3.3.1]nonane ring system, which constitutes the core of the RNA polymerase inhibitor tagetitoxin, has been achieved through cyclisation of a thiol onto an electrophilic ketone.
