Active ion transporters from readily accessible acyclic octapeptides containing 3-aminobenzoic acid and alanine†,10.1039/C3CC44224A

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Active ion transporters from readily accessible acyclic octapeptides containing 3-aminobenzoic acid and alanine†

Bahiru P. Benke,Nandita Madhavan

Chemical Communications Pub Date : 06/24/2013 00:00:00 , DOI:10.1039/C3CC44224A

Abstract

Ion transporters have been developed from acyclic octapeptides comprising L/D alanine and m-aminobenzoic acid. These octapeptides transport cations up to 3 times faster than their cyclic analog through lipid vesicles. Preliminary CD, XRD and computational studies allude to a 6–9 Å wide tetrameric ion channel as the active ion transporter.