AlCl3-catalyzed [3 + 3] cycloaddition of chalcones and β-enamine ketones (esters): a highly efficient access to multisubstituted cyclohexa-1,3-dienamines†
Meng-Ming Xing,Hui Xu,Li-Fen Hou,Jian-Rong Gao,Yu-Jin Li
AlCl3-catalyzed [3 + 3] intermolecular cycloaddition of enones with enamines is described. This efficient protocol was successfully achieved to give 1,3-cyclohexadiene derivatives in good to excellent yields.
![Graphical abstract: AlCl3-catalyzed [3 + 3] cycloaddition of chalcones and β-enamine ketones (esters): a highly efficient access to multisubstituted cyclohexa-1,3-dienamines](http://hg.y866.cn/compound/lib/scimg/usr/1/C5RA25691G.jpg)
