In order to develop a new silane coupling agent that can be used as coupling agent and initiator, (3-(tert-butylperoxy)propyl)trimethoxysilane was synthesized by using tert-butyl hydroperoxide and (3-chloropropyl) trimethoxysilane. The new reagent was characterized by ¹H-NMR, FT-IR and mass spectroscopy. The thermokinetics of the new reagent was investigated, including thermal stability, decomposition constants (K_d), activation energy (E_a), the heat of decomposition (ΔH) and pre-exponential factor (A_d). In addition, the application of (3-(tert-butylperoxy)propyl)trimethoxysilane on modificating nano-TiO₂ and initiating polymerization was studied. The structures of the products of modificating nano-TiO₂ and initiating polymerization were verified by XPS, FT-IR. The results indicated that the new reagent had the characteristics of a coupling agent and initiator.