Synthesis of cyclohexylidenehydrazine-fused polycyclics via a photocatalytic radical cascade reaction of 2-ethynylaldehyde hydrazones†,10.1039/C6CC09863K

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Synthesis of cyclohexylidenehydrazine-fused polycyclics via a photocatalytic radical cascade reaction of 2-ethynylaldehyde hydrazones†

Nengneng Zhou,Jing Liu,Zhongfei Yan,Zhongkai Wu,Honglin Zhang,Weipeng Li

Chemical Communications Pub Date : 01/18/2017 00:00:00 , DOI:10.1039/C6CC09863K

Abstract

A general and efficient visible-light photoredox-catalyzed cascade annulation of 2-ethynylaldehyde hydrazones with α-bromo-carbonyls for the synthesis of various cyclohexylidene-hydrazine-fused polycyclic compounds is described. This protocol is characterized by a broad substrate scope, mild conditions and amenability to gram-scale synthesis.