TMSCFX2 (X = Cl, Br) as halofluorocarbene sources for the synthesis of halofluorocyclopropanes†,10.1039/D0CC06004F

批量搜索

批量搜索

热搜：

Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

TMSCFX2 (X = Cl, Br) as halofluorocarbene sources for the synthesis of halofluorocyclopropanes†

Zili Fan,Ling Huang,Kaili Gao,Chuanfa Ni

Chemical Communications Pub Date : 12/08/2020 00:00:00 , DOI:10.1039/D0CC06004F

Abstract

TMSCFX₂ (X = Cl, Br; TMS = trimethylsilyl) have been developed as halofluorocarbene (CFX, X = Cl, Br) precursors for [2+1] cyclopropanation with alkenes. Structurally diverse halofluorocyclopropanes were obtained in good to excellent yields. It was found that the reactivity order of the three halofluorocarbene reagents (TMSCF₂Br, TMSCFCl₂, and TMSCFBr₂) in halofluorocyclopropanation with 1,1-diphenylethylene can be very different under different reaction conditions.