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Synthesis of polysubstituted 3,4-dihydro-2H-thiopyrans by regioselective annulation of 3,3-disubstituted allylic alcohols with a β-oxodithioester†
Srinivas Kurva,Vinodkumar Sriramoju,Sridhar Madabhushi,Jagadeesh Babu Nanubolu
New Journal of Chemistry Pub Date : 10/09/2017 00:00:00 , DOI:10.1039/C7NJ03025H
Abstract

Polyfunctionalized 3,4-dihydro-2H-thiopyrans were obtained in high yields via the regioselective annulation of 3,3-disubstituted allylic alcohols with a β-oxodithioester under BF3·Et2O catalysis.

Graphical abstract: Synthesis of polysubstituted 3,4-dihydro-2H-thiopyrans by regioselective annulation of 3,3-disubstituted allylic alcohols with a β-oxodithioester
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