Synthesis of unprotected and borane-protected cyclic phosphines using Ru– and Mo– based olefin metathesis catalysts†,10.1039/B306940K

批量搜索

批量搜索

热搜：

Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Synthesis of unprotected and borane-protected cyclic phosphines using Ru– and Mo– based olefin metathesis catalysts†

Catherine A. Slinn,Alison J. Redgrave,S. Lucy Hind,Chris Edlin,Steven P. Nolan,Veronique Gouverneur

Organic & Biomolecular Chemistry Pub Date : 09/10/2003 00:00:00 , DOI:10.1039/B306940K

Abstract

Ru– and Mo-based catalysts can be used in ring closing metathesis (RCM) reactions to synthesise cyclic phosphines protected as their borane complexes. The compatibility of the Schrock Mo-catalyst and the N-heterocyclic carbene Ru-catalysts with this class of substrates is particularly noteworthy as asymmetric RCM (ARCM) is now emerging as a new tool for the preparation of homochiral phosphines. One of the key results is that the Mo-catalyst allows the ring closure of the unprotected diallylphenylphosphine with 95% conversion.