TFAA/H3PO4 mediated unprecedented N-acylation of carbazoles leading to small molecules possessing anti-proliferative activities against cancer cells†,10.1039/C4OB00686K

热搜：

Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

TFAA/H3PO4 mediated unprecedented N-acylation of carbazoles leading to small molecules possessing anti-proliferative activities against cancer cells†

Sunder Kumar Kolli,Bagineni Prasad,P. Vijaya Babu,Mohd Ashraf Ashfaq,Nasreen Z. Ehtesham,R. Ramesh Raju,Manojit Pal

Organic & Biomolecular Chemistry Pub Date : 07/01/2014 00:00:00 , DOI:10.1039/C4OB00686K

Abstract

For the first time TFAA/H₃PO₄ has facilitated the direct and metal-free N-acylation of carbazoles leading to a number of N-acylated derivatives. Several of these compounds were found to be promising when tested for their anti-proliferative properties against oral cancer cell lines.