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Tandem enzyme-catalysed oxidations of alkyl phenyl sulfides and alkyl benzenes: enantiocomplementary routes to chiral phenols
Narain D. Sharma,Vera Ljubez,Breige E. Byrne,Steven D. Shepherd,Christopher C. R. Allen,Michael J. Larkin,Howard Dalton
Chemical Communications Pub Date : 07/29/2002 00:00:00 , DOI:10.1039/B205903G
Abstract

Dioxygenase-catalysed trioxygenation of alkyl phenyl sulfides and alkyl benzenes yields enantiopure cis-dihydrodiol sulfoxides and triols respectively; naphthalene cis-dihydrodiol dehydrogenase-catalysed aromatisation of these diastereoisomers gives enantiopure catechols of either configuration.

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