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Ultrasensitive nucleic acid detection using confocal laser scanning microscope with high crystalline silverdendrites†
Xuan Yang,Xuping Sun,Zhaozi Lv,Weiwei Guo,Yan Du,Erkang Wang
Chemical Communications Pub Date : 10/18/2010 00:00:00 , DOI:10.1039/C0CC03280H
Abstract

A new kind of silver micro-dendrites with no surfactants protected has been synthesized for the separation and detection of DNA merely by earth gravity as the density of silver is larger than that of water. Through this approach, the DNA of human T-lymphotropic virus type I (HTLV-I) can be detected down to 10 pM with the detection range from 10 pM to 100 nM.

Graphical abstract: Ultrasensitive nucleic acid detection using confocal laser scanning microscope with high crystalline silver dendrites
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