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Using aptamers evolved from cell-SELEX to engineer a molecular delivery platform†
Prabodhika Mallikaratchy,Haipeng Liu,Yu Fen Huang,Hui Wang,Dalia Lopez-Colon,Weihong Tan
Chemical Communications Pub Date : 04/09/2009 00:00:00 , DOI:10.1039/B823258J
Abstract

We report a chemically modified construct of the Sgc8 aptamer, selected against CEM cells, conjugated to an activator platform for stimulated release of molecules at the tumor surface using DNA template assisted functional group transfer reactions (DTGTR).

Graphical abstract: Using aptamers evolved from cell-SELEX to engineer a molecular delivery platform
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