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The transition-metal-catalyst-free oxidative homocoupling of organomanganese reagents prepared by the insertion of magnesium into organic halides in the presence of MnCl2·2LiCl†
Zhihua Peng,Na Li,Xinyang Sun,Fang Wang,Lanjian Xu,Cuiyu Jiang,Linhua Song,Zi-Feng Yan
Organic & Biomolecular Chemistry Pub Date : 08/08/2014 00:00:00 , DOI:10.1039/C4OB01235F
Abstract

Organomanganese reagents were prepared by the insertion of magnesium into aryl halides in the presence of MnCl2·2LiCl. These organomanganese reagents smoothly undergo 1,2-addition, acylation, and Pd-catalyzed cross-coupling with various electrophiles. Especially, the oxidative homocoupling of organomanganese reagents was completed in one pot without an additional transition-metal catalyst.

Graphical abstract: The transition-metal-catalyst-free oxidative homocoupling of organomanganese reagents prepared by the insertion of magnesium into organic halides in the presence of MnCl2·2LiCl
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