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Visible light-induced intermolecular radical addition: facile access to γ-ketoesters from alkyl-bromocarboxylates and enamines†
Bei Hu,Haixia Chen,Yan Liu,Wuheng Dong,Kai Ren,Xiaomin Xie,Hao Xu,Zhaoguo Zhang
Chemical Communications Pub Date : 09/04/2014 00:00:00 , DOI:10.1039/C4CC05590J
Abstract

A highly efficient addition of alkyl α-bromocarboxylates to enamines by visible light-induced photoredox catalysis is reported. Compared with traditional methods, the reaction described here provided an alternative route for the construction of valuable γ-ketoesters in generally good yields.

Graphical abstract: Visible light-induced intermolecular radical addition: facile access to γ-ketoesters from alkyl-bromocarboxylates and enamines
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