γ-AApeptide-based small-molecule ligands that inhibit Aβ aggregation†
Haifan Wu,Yaqiong Li,Ge Bai,Youhong Niu,Qiao Qiao,Jeremiah D. Tipton,Chuanhai Cao,Jianfeng Cai
Chemical Communications Pub Date : 10/10/2013 00:00:00 , DOI:10.1039/C3CC46685J
Abstract
We report the design, synthesis, characterization and evaluation of a novel class of γ-AApeptide one-bead-one-compound (OBOC) library, from which a small γ-AApeptide was identified to effectively prevent and disassemble Aβ aggregation.
