The use of calcium carbide in one-pot synthesis of symmetric diaryl ethynes†
Weiwei Zhang,Huayue Wu,Zhiqing Liu,Ping Zhong,Lin Zhang,Xiaobo Huang,Jiang Cheng
Chemical Communications Pub Date : 10/02/2006 00:00:00 , DOI:10.1039/B607809E
Abstract

An efficient Pd-catalyzed copper and amine free coupling reaction of acetylene and aryl bromides was achieved with calcium carbide as an acetylene source, using inorganic base and easily prepared, air-stable aminophosphine ligand in common organic solvents, providing symmetric diaryl ethynes in one-pot with yields ranged from moderate to excellent.

Graphical abstract: The use of calcium carbide in one-pot synthesis of symmetric diaryl ethynes