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Vinyl esters as effective acetaldehyde surrogates in [4 + 1] cycloaddition based multicomponent cascade†
Manoj Kumar,Sourav Bagchi,Anuj Sharma
RSC Advances Pub Date : 06/11/2015 00:00:00 , DOI:10.1039/C5RA10073A
Abstract

A new multicomponent cascade has been designed by utilizing vinyl esters as effective acetaldehyde surrogate. While most of the cyclic α-ketoenols underwent a facile three component conversion to annulated furans, phenols such as naphthol and sesamol got simply acylated under the same reaction conditions. This microwave assisted method provides clean access to a wide range of functionalised furans in a short span of time.

Graphical abstract: Vinyl esters as effective acetaldehyde surrogates in [4 + 1] cycloaddition based multicomponent cascade
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