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Vinylic amino group activation: a new and general strategy leading to functionalized fused heteroaromatics†
Rajnikanth Sunke,Raju Adepu,Ravikumar Kapavarapu,Swetha Chintala,Chandana Lakshmi Teja Meda,Kishore V. L. Parsa,Manojit Pal
Chemical Communications Pub Date : 03/13/2013 00:00:00 , DOI:10.1039/C3CC41337C
Abstract

A conceptually new and general strategy has been developed for the construction of a benzimidazole or a benzoxazole ring fused with isoquinolinone affording a diverse and unique class of small molecules as potential and novel inhibitors of PDE4.

Graphical abstract: Vinylic amino group activation: a new and general strategy leading to functionalized fused heteroaromatics
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