Silica-coated magnetic NiFe₂O₄ nanoparticle-supported Preyssler heteropolyacid (H₁₄[NaP₅W₃₀O₁₁₀]) catalyzed efficiently the synthesis of highly substituted pyran derivatives under ultrasonic irradiation at room temperature in ethanol. In comparison with conventional methods, our protocol is convenient and offers several advantages, such as shorter reaction times, higher yields, milder conditions and environmental friendliness. The catalyst can be recovered by a simple external magnet and used four times without a significant loss of catalytic activity.