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Transition metal-free generation of the acceptor/acceptor-carbene via α-elimination: synthesis of fluoroacetyl cyclopropanes†
Yongdong Wang,Jing Han,Jie Chen
Chemical Communications Pub Date : 04/22/2016 00:00:00 , DOI:10.1039/C6CC01576J
Abstract

An efficient transition metal-free approach for the generation of acceptor/acceptor-carbene followed by trapping with alkenes to provide fluoroacetyl cyclopropanes has been described. The resulting cyclopropanes could be further converted into the fluoromethyl dihydrofurans or fluorodihydropyrroles through ring-expansion processes.

Graphical abstract: Transition metal-free generation of the acceptor/acceptor-carbene via α-elimination: synthesis of fluoroacetyl cyclopropanes
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