Copper ligation to soluble oligomers of the English mutant of the amyloid-β peptide yields a linear Cu(i) site that is resistant to O2 oxidation†
Kristy L. Peck,Heather S. Clewett,Jennifer C. Schmitt,Jason Shearer
Chemical Communications Pub Date : 04/23/2013 00:00:00 , DOI:10.1039/C3CC40326B
Abstract
Copper coordination to soluble oligomers of the English (AβH(6)R) mutant of the amyloid-β peptide is probed. Cu(II) coordination yields a square planar (N/O)4 coordination environment, while reduction yields an O2 inert linear bis-His Cu(I) centre.
