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First example of a Prins–Ritter reaction on terpenoids: a diastereoselective route to novel 4-amido-octahydro-2H-chromenes†
Barnali Sarmah,Gakul Baishya,Rajani K. Baruah
RSC Advances Pub Date : 04/29/2014 00:00:00 , DOI:10.1039/C4RA02124J
Abstract

(−)-Isopulegol was subjected to a triflic acid-promoted three-component Prins–Ritter reaction with a series of aldehydes to produce a library of novel 4-acetamido-octahydro-2H-chromene derivatives in good yields and high diastereoselectivities.

Graphical abstract: First example of a Prins–Ritter reaction on terpenoids: a diastereoselective route to novel 4-amido-octahydro-2H-chromenes
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