Background: Wound healing remains a challenge that has not yet been solved. Researchers are more interested in gold nanoparticles (AuNPs) than other nanoparticles because of their size-related chemical, electrical, and magnetic properties that may be useful in biological applications. Due to their antioxidant, anti-inflammatory, antibacterial qualities, and their capacity to destroy free radicals, AuNPs are also advantageous in lowering inflammation and promoting quicker wound healing. Method: In this study, we analyzed all pertinent papers up to April 2021 to study the impact of AuNPs on the wound healing process in animal experiments based on scientific data, as wound healing is still one of the most significant medical difficulties. Based on the keywords