Identification using LC-MSn of co-metabolites in the biosynthesis of the polyketidetoxinmycolactone by a clinical isolate of Mycobacterium ulcerans†
Hui Hong,Paul J. Gates,James Staunton,Tim Stinear,Stewart T. Cole,Jonathan B. Spencer
Chemical Communications Pub Date : 10/20/2003 00:00:00 , DOI:10.1039/B308163J
Abstract
LC-MSn analysis of mycolactonetoxin from extracts of Mycobacterium ulcerans has shown that minor co-metabolites, including two previously unreported, differ structurally from mycolactone only in a small portion of the polyketide side-chain.
