Induction of chirality: experimental evidence of atropisomerism in azapeptides†
Philipp A. Ottersbach,Gregor Schnakenburg,Michael Gütschow
Chemical Communications Pub Date : 04/18/2012 00:00:00 , DOI:10.1039/C2CC31161E
Abstract
Methylation of the peptide bond in model azadipeptides leads to the E configuration and hence to atropisomerism due to a restricted rotation around the N–N axis.
