Intramolecular Michael addition reaction for the synthesis of benzylbutyrolactones†
Hu He,Li-Xin Dai,Shu-Li You
Organic & Biomolecular Chemistry Pub Date : 05/20/2010 00:00:00 , DOI:10.1039/B924770J
Abstract

A convenient synthesis of benzyl-γ-butyrolactone derivatives via intramolecular Michael addition reaction of nitro-substituted aryl allyl β-ketocarboxylates is reported. The method features simple operation, mild reaction conditions and high efficiency.

Graphical abstract: Intramolecular Michael addition reaction for the synthesis of benzylbutyrolactones