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Microbial biosynthesis of medicinally important plant secondary metabolites
Eun Ji Kim,Eunji Kim,Kris Rathwell,Sang-Jip Nam,Yeo Joon Yoon
Natural Product Reports Pub Date : 07/29/2014 00:00:00 , DOI:10.1039/C4NP00057A
Abstract

Covering: up to 2014

Secondary metabolites derived from plants are a valuable source of pharmaceuticals, nutraceuticals, and cosmetics. To harness the potential of these natural products, reliable methods must be developed for their rapid and sustainable resupply. Microbial production of plant secondary metabolites through the heterologous expression of plant biosynthetic genes represents one such solution. This highlight focuses on recent advances in the microbial biosynthesis of plant secondary metabolites including terpenoids, flavonoids, and alkaloids as well as providing a brief insight into the current limitations and future prospects.

Graphical abstract: Microbial biosynthesis of medicinally important plant secondary metabolites
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