Modulation of raft domains in a lipid bilayer by boundary-active curcumin†,10.1039/C3CC47738J

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Modulation of raft domains in a lipid bilayer by boundary-active curcumin†

Manami Tsukamoto,Kenichi Kuroda,Ayyalusamy Ramamoorthy,Kazuma Yasuhara

Chemical Communications Pub Date : 12/16/2013 00:00:00 , DOI:10.1039/C3CC47738J

Abstract

The function and mode of action of curcumin in modulating the formation of lipid raft domains were investigated by microscopic observation using model membranes. Curcumin induces fusion of lipid raft domains at extremely low concentrations through the alteration of the boundary between the ordered and disordered phases.