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Monacolin N, a compound resulting from derailment of type I iterative polyketide synthase function en route to lovastatin
John L. Sorensen,John C. Vederas
Chemical Communications Pub Date : 05/23/2003 00:00:00 , DOI:10.1039/B304252A
Abstract

A novel compound, monacolin N, has been isolated from fermentation cultures of Aspergillus nidulans in which the lovastatin polyketide synthase genes lovB and lovC are heterologously expressed.

Graphical abstract: Monacolin N, a compound resulting from derailment of type I iterative polyketide synthase function en route to lovastatin
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